Well, it about killed me, but I figured it out.
For starters, my qemu-kvm virtual machine would not run 22H2, but I finally manually configured it and solved the issue. The symptom was that the VM could not boot off the 22H1 ISO and solving that solved the new 22H2 boot method and the SAFE_OS error.
The corrected XML file can be found over on:
https://gitlab.com/qemu-project/qemu/uploads/c94506037990fdc475a7c76e624af33...