Hi,
I start the Live OS of F39 (Fedora-Workstation-Live-x86_64-39_Beta-1.1.iso) on a system
that requires a display orientation of "Portrait Right".
As soon as I change the display orientation, the mouse stops working.
When I do the same with the Live OS of Fedora 38, all works fine.
Hence, I consider this an F39 beta bug.
-RL.