Off the top of my head the tools that are either completely broken or partially broken on Wayland that work fine on X11.
* Google Meet
* Zoom
* MS Teams
* Slack screen sharing
* Discord screen sharing
and then there are the various broken desktop sharing apps:
* TeamViewer
* AnyDesk
* Chrome Remote Desktop
* x11vnc
* many more
and then there are the various niche products for the developer community with smaller communities but are nonetheless startups who see a market opportunity:
* Pop (
https://pop.com/) -- works only on X11 for now, seems they are having issues with implementing Wayland, especially screen control
* Pair-programming tools built into products like JetBrains IDEs
I don't think the user population represented by these and others is shrinking at all -- on the contrary, it's growing by leaps and bounds, and any one just the top 6 above likely boasts user communities thousands of times larger than the data scientists who use rstudio-server and Jupyter via browser.